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Moreover, a element of endothelial dysfunction has been proposed, which may contribute to irregular vessel reactivity. However, testosterone in physiologic doses may even be helpful in patients with angina , have larger ischemic thresholds and improved quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and will increase coronary blood flow in males with established coronary artery illness . Therefore, an interaction of endogenous elements of the patient’s threat profile in addition to the testosterone dosing could also be problems with whether or not antagonistic occasions occur.
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Rhoden EL, Morgentaler A. Risks of testosterone-replacement remedy and proposals for monitoring. Testosterone substitute in hypogonadal males with angina improves ischaemic threshold and quality of life. Ajayi AAL, Mathur R, Halushka PV. Testosterone improve human platelet thromboxane A2 receptor density and aggregation responses.
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We report a case of an acute ST-segment elevation myocardial infarction in a patient with conventional cardiac danger factors utilizing supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this patient additionally had polycythemia, doubtless secondary to high-dose testosterone. The patient underwent profitable percutaneous intervention of the best coronary artery. Physicians and patients ought to concentrate on the scientific penalties of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).
Siamo spiacenti, il commento forma è chiusa in questo momento.